Phytochemical Characterization and Antioxidant Bioactivity of Andrographis paniculata (Nees)
نویسندگان
چکیده
Background: Medicinal plants are natural sources of antioxidants effective in the treatment radical mediated diseases. This study evaluated in-vitro antioxidant and phytochemical constituents methanolic leaves extract Andrographis paniculata . Methods: Fresh A. were harvested from a local far m, air -dried extracted with methanol. Chemical composition, activities, α-amylase enzyme inhibitory potentials determined Results: The concentration-dependently scavenges 2,2-Diphenyl-1-picrylhydrazyl (DPPH) 2,2’azinobis (3-ethylbenzothiazoline-6-sulphonic acids) (ABTS) radicals. It nitric oxide radicals IC50 145.99 μg/ml compared to 167.17 standard ascorbic acid has 41% activity ferric reducing power. also inhibited induction lipid peroxidation α-Amylase concentration-dependent manner. assays employed revealed presence various phytochemicals extract. Further analysis gas-chromatography possible Andrographolide, Deoxyandrographolide, Apigenin, Kaempferol, Quercetin, Methyl vanillate, Caffeate, Beta-sitosterol, Vanillic total phenolics content was found be 29.11mg GAE/g, proximate moisture content, crude protein, fat, fiber, ash, Nitrogen free 21.89%, 5.66%, 8.74%, 0.95%, 6.87%, 55.89% respectively. Conclusion: plant demonstrated good contain phytochemicals. Therefore, it could inferred that effectiveness as medicinal due compounds plant.
منابع مشابه
Characterization studies on medicinal plant of Andrographis paniculata (NEES)
Andrographis paniculata (Nees), is a valuable traditional medicinal plant and it has many important bioactive compounds. It cures and prevents a number of diseases in human beings. It is a boon of the nature of human healthy life. It cures cold, fever, colic pain, active against inflammatory, antidiabetic activity, antioxidant, antifertility, cardiovascular and anti-virus including inhibited HI...
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ژورنال
عنوان ژورنال: Pan African Journal of Life Sciences
سال: 2021
ISSN: ['2672-5924']
DOI: https://doi.org/10.36108/pajols/1202.50.0220